Drugs that have restrictions apart from prior authorization, quantity restrictions, and action therapy associated with each prescription.

pentobarbital increases toxicity of ifosfamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. CYP3A4 inducers may increase the metabolism of ifosfamide to its Lively alkylating metabolites.

pentobarbital will reduce the extent or effect of cariprazine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

Watch Closely (one)pentobarbital will decrease the level or impact of hydrocodone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Warning when discontinuing CYP3A4 inducers which might be coadministered with hydrocodone; plasma concentrations of hydrocodone may well maximize and may end up in potentially fatal respiratory depressionSerious - Use Substitute (1)hydrocodone, pentobarbital.

pentobarbital will lessen the level or outcome of almotriptan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will minimize the extent or impact of methylprednisolone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

buprenorphine, extended-acting injection and pentobarbital equally raise sedation. Steer clear of or Use Alternate Drug. Limit use to sufferers for whom choice treatment selections are insufficient

pentobarbital will lessen the extent or impact of aprepitant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

pentobarbital raises toxicity of ifosfamide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. CYP3A4 inducers might improve the metabolism of ifosfamide to its Lively alkylating metabolites.

pentobarbital will reduce the level or result of isradipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unfamiliar.

Workout warning when administered to clients with acute or chronic agony; could bring about paradoxical exhilaration or critical signs and symptoms may be masked

Data are at this time not available to Examine impact of barbiturates when forceps delivery or other intervention is important; also, information are not out there to find out the result of such barbiturates within the later on development, progress, and practical maturation of the child

Overdose. It's also wise to talk with your health care provider before raising your dose. Taking far too much of a CNS depressant may lead to an overdose. When you have indications of an overdose, get more info like your ability to breathe slows or stops, find immediate clinical interest.

Check Closely (one)pentobarbital will lessen the level or result of benzhydrocodone/acetaminophen by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Caution when discontinuing CYP3A4 inducers which can be coadministered with benzhydrocodone (prodrug of hydrocodone); plasma concentrations of hydrocodone might boost and may lead to most likely fatal respiratory depression.